Rootine Review: How Does This Personalized Vitamins Service Work?

Written by Samantha Odake | Last updated:


Rootine offers DNA and blood testing and a personalized supplement service. Users can purchase tests or upload past results to receive access to their supplement formula. Test prices range from $99 to $178, and personalized vitamins cost $69/month for 3 months. Only available in the United States.


  • Analyzes DNA and lab data.
  • Option to upload a raw DNA file and past lab results.
  • Fast turnaround time.


  • Only looks at around 50 genetic variants and fewer lab markers.
  • Does not offer lifestyle or diet suggestions; limited to supplement recommendations.
  • Tests and supplements are only available in the US.
  • Only accepts raw data from 23andMe and Ancestry.

About Rootine

Rootine was founded in 2018 by Rachel Sanders and Dr. Daniel Wallerstorfer. The company is headquartered in Nashville, Tennessee. They received $3.1 million in funding over 2 rounds, with the latest funding round being in August 2021.

Review of Rootine Products & Features

Rootine offers DNA and blood tests for vitamins and minerals users can take at home, and provides personalized vitamin formulas based on the results. To get started, customers need to answer a questionnaire about their lifestyle and health habits, which the company claims to take into consideration when recommending supplements.

The DNA test analyzes around 50 genetic variations related to nutrition to help you understand how your body absorbs and processes nutrients. According to the company, DNA results impact the supplement dosage recommendations.

Rootine also offers two options for blood tests. The Vitamins Blood Test analyzes vitamin B9 (folate), B12, D, hsCRP, and homocysteine levels, while the Minerals Blood Test looks at magnesium, copper, zinc, selenium, cadmium, and mercury levels.

DNA test results are ready within 3 to 5 weeks, while lab results are available within 5 days from your sample arriving at the lab.

Users also have the option to upload a raw DNA file from 23andMe or Ancestry and past lab results to receive their supplement recommendations.

Interested in using DNA, labs, and lifestyle data to optimize your health? Upload your DNA to SelfDecode to discover personalized health insights and an all-in-one supplement formula tailored to your genes

Rootine Vitamins

Rootine vitamins can include up to 19 nutrients, with dosages varying according to test results and questionnaire answers. Vitamins are delivered in individual daily packets in the form of microbeads.

Review of Rootine Reports

After signing up and answering the lifestyle questions, you will gain access to the Rootine dashboard. You can upload DNA and blood test results or order tests and supplements directly from the platform.

Rootine dashboard

As can be seen in the screenshot above, users have the option to navigate through DNA and lab results, or order vitamins directly. The company also displays the next steps for each user.

Keep in mind Rootine requires you to manually upload each lab marker value to their platform. Below you can view the interface for past lab results upload. Alternatively, you can order blood tests from the company.

Rootine Blood Test

The DNA test results include information related to different nutrients and health topics, and are divided into 15 trait reports. The categories include:

  • Selenium
  • Bones
  • Metabolism
  • Detox
  • Brain
  • Heart Health
  • And others

Rootine explains your body’s ability to absorb or process certain vitamins and minerals and provides nutrient recommendations. The report also includes which genes influence the specific trait and the scientific references to support this information.

You can view a sample report below.

Rootine DNA test

As demonstrated above, Rootine limits their recommendations to nutrient intake and does not provide lifestyle or diet suggestions to help users counteract the negative effects of their genes.

After the health data has been analyzed, Rootine displays a custom supplement formula on the dashboard, which can include up to 19 nutrients.

Supplements are offered on a subscription base, although the company claims users can pause or cancel at any time.

Below you can view a sample formula for a Rootine vitamin.

Rootine Vitamin Formula

Rootine Cost

Rootine vitamins cost $69 per month for 3 months. Tests are priced as follows:

  • DNA Test ($99)
  • Blood Vitamin Test ($99)
  • Blood Mineral Test ($119)
  • DNA + Blood Test Bundle ($178)

Rootine Privacy & Data Security

Rootine claims to use reasonable methods to protect user information. Genetic data is stored separately from personally identifiable information. They state they destroy samples after analysis. Users can terminate their account at any time, in which case the company claims to remove all of your genetic and personal information within 30 days.

Health Recommendations from Rootine

Rootine claims to offer personalized supplement formulas based on DNA, blood, and lifestyle data. The company does not provide diet or lifestyle recommendations to help users improve their health. Their suggestions are solely based on nutrition-related health markers.

Rootine Reviews

Unfortunately, there are not many Rootine reviews from customers available on third-party websites, so it can be difficult to assess the general public opinion regarding the company. They do not have a Facebook page, and interactions on other social media are minimal.

Alternatives to Rootine

Rootine’s approach of combining DNA and blood tests to offer personalized supplement formulas is a good one, albeit they may lack when it comes to the number of DNA and lab markers analyzed. Currently, the DNA test looks at 50 genetic variants, while the blood tests only analyze a handful of vitamins and minerals.

For a more comprehensive approach to health, SelfDecode could be a good alternative. You can upload your DNA file to receive insights into your genetic predispositions and personalized diet, lifestyle, and supplement recommendations based on your unique DNA.

Discover your personalized all-in-one supplement formula designed for your unique genes to help you address your health issues.

By signing up, you will also have access to a lab analyzer for insights into over 1,000 lab markers. Upload your past test results to find out where your levels are from their optimal range and track them over time.

SelfDecode gives you detailed explanations of each lab marker, and what possible health effects you may experience from suboptimal levels.

SelfDecode also offers cutting edge ancestry analysis with in-depth ethnicity percentage breakdown, as well as a color-coded map that can help you easily discover where you’re from. You’ll be able to trace your maternal lineage back through the ages, learning where they started in the world, and the journey that they took to get to where you are today. Ancestry Insights is only available with a SelfDecode DNA kit.


SelfDecode Rootine Vitl Vitagene
Personalized & holistic health recommendations Yes Yes (limited) Yes (limited) No
Product Free DNA and lab analysis, DNA and lab testing, wellness reports, personalized health recommendations, personalized supplement formula, ancestry DNA and blood testing, personalized vitamins DNA and blood testing, personalized vitamins service DNA and at-home health testing, diet, fitness, skin, and supplement reports
Genes & lab markers analyzed Up to 83 million genetic variants and over 1,000 lab markers Around 50 genetic variants and 11 lab markers Around 40 genes and 10 blood markers A few SNPs per report
Raw data access Yes Yes Yes Yes
Cost (USD) Start Free

Plans from $99-$249

$99 – $178 for tests

$69/month for vitamins

$60 – $135 for tests

$14 – $33+ per month for supplements

$49 – $139+

Rootine Review Summary

Rootine combines DNA and blood test results to provide supplement formulas users can purchase to address potential nutrient deficiencies. However, recommendations are based on only 50 genetic variants and fewer lab markers. This means you might be missing out on many that may affect your overall health.

Rootine does use DNA and blood test results to generate recommendations, but it’s important to note that they only look at health markers related to nutrition and nutrient absorption, so you’ll only receive a snippet of how your health truly is.

Other alternatives such as SelfDecode analyzes millions of genetic variants and over 1,000 lab markers to provide personalized diet, lifestyle, and supplement recommendations tailored to you. Discover your genetic predispositions and explore a personalized supplement formula designed to help you optimize your health.

You can upload your DNA to SelfDecode for free to get started.

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